Principal Scientist - EnzymologyCambridgePermanentSRG are currently supporting the search for a Principal Scientist with an expertise in enzymology.You will be an inspirational scientist with an exceptional record of bringing your deep knowledge of enzymology and biochemistry to impact on projects. Within this role you will be brining scientific leadership to the design of biochemical assays and bespoke mechanistic data helping to characterise cancer targets.The successful candidate will have a recent background in the mechanistic study of enzymes, assay development, and leadership experience within the drug discovery field (compound handling, mechanism of inhibition studies). You will need to demonstrate leadership capabilities, driving innovation and strategic decision making. The Role:Provide scientific leadership to define and implement best practice for biochemical assays and bespoke mechanism of action studies.Design and develop novel physiologically relevant biochemical assays for a range of target classes, using recombinant proteinsCharacterise cancer targets in detail at the molecular levelDefine biochemical profiling cascade to support characterisation of novel small molecules for oncology targetsCharacterise small molecules in vitro using recombinant proteins and a range of biochemical assay technologies, with a particular focus on detailed kinetic and mechanism of inhibition studies and their translation into the cellular environment.Represent the department acros